Original Article. Inherited DNARepair Gene Mutations in Men with Metastatic Prostate Cancer. Colin C. Pritchard, M. D. , Ph. D. , Joaquin Mateo, M. D. , Michael F. Walsh.
Miki et al. (1994) determined that the BRCA1 gene contains 22 exons spanning about 110 kb of DNA. Brown et al. (1996) determined the detailed structure of the BRCA1.
Original Article. Inactivation of the DNARepair Gene MGMT and the Clinical Response of Gliomas to Alkylating Agents. Manel Esteller, M. D. , Ph. D. , Jesus Garcia.
A gene is a sequence of DNA or RNA which codes for a molecule that has a function. The DNA is first copied into RNA. The RNA can be directly functional or be the.
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Stayton et al. (1994) described the cloning and characterization of a gene, provisionally called Xlinked helicase2 (XH2), located on chromosome Xq13.
Cells are constantly under threat from the cytotoxic and mutagenic effects of DNA damaging agents. Environmental DNAdamaging agents include UV light and ionizing
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Zincfinger nucleases (ZFNs) are artificial restriction enzymes generated by fusing a zinc finger DNAbinding domain to a DNAcleavage domain. Zinc finger domains can.